Methandienone is an anabolic steroid banned from use by FDA under controlled substances act. Dianabol has been very popular in bodybuilders until its ban to increase strength and volume of their muscles. Dianabol acts strongly on androgen receptors and exerts its effects by protein synthesis and glycogen breakdown to increase muscle mass in short space of time. Dianabol produces estrogen as end product so water retention is also one of the contributors towards weight gain and increased volume. Dianabol effective dose is15-50 mg/day in men and its active life is 6-8 hours. Dianabol is excreted through kidneys and detection time in urine is 5-6 weeks. Until the ban Dianabol has been used as tonic by bodybuilders. Probably, Dianabol is effective in treatment of senile postmenopausal osteoporosis. Dianabol was also recommended in those individuals who are suffering from condition called pituitary deficient dwarfism. Dianabol was also used in those individuals who have weakened bones and always complain for exhaustion after small running and prolong walking. Still, Dianabol is prepared in large quantity in those countries where drugs regulations are weak and is used in human as well as in veterinary patients of the conditions described above.
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When taken for more than 4-6 weeks, it can increase body mass and protein anabolism. However, buy testosterone cypionate uk for the body to build muscle one also has to eat a diet rich in calories. Most bodybuilders also take a combination of other hormones at the same time. Because testosterone is converted to estrogen in the fatty tissues, there is always the chance of developing gynecomastia and water retention. To prevent this, most bodybuilders add Arimidex or tamoxifen during the off cycle.
During testosterone injections, the natural body testosterone release is inhibited by feedback mechanism through inhibition of pituitary LH. At large doses, even spermatogenesis can be impaired. To allow for the hypothalamic-pituitary axis to recover, it is highly recommended that the drug be tapered off slowly over a period of a few weeks. Sudden discontinuation of the drug can lead to extreme fatigue clit tumblr , weight loss and susceptibility to fractures.