Intralesional corticosteroids injection

Yang et al (2015) stated that peri-orbital microcystic lymphatic malformations (LM) can cause severe symptoms, such as blepharoptosis, amblyopia, chemosis, strabismus, diminished vision, and blindness.  In a retrospective study, these researchers evaluated the clinical outcome in peri-orbital microcystic LM patients with blepharoptosis who underwent surgical treatment combined with intralesional bleomycin injection.  A total of 9 patients diagnosed as peri-orbital microcystic LM with blepharoptosis were included in this study.  All of them underwent surgical treatment and bleomycin injection from January 2010 to January 2014.  The lesion was resected through the lower eyebrow and/or a coronal incision at the first stage, and levator resection was performed at the second stage.  Any persistent lesion or its recurrence was managed by intralesional bleomycin injection.  Blepharoptosis and visual obstruction were corrected in all patients.  Mean follow-up was months; 6 patients had recurrence during follow-up; and 2 patients who had partial eyelid closure after the second stage surgery recovered in 3 months.  Amblyopia, astigmatism, and strabismus were not improved after treatment.  All patients had excellent aesthetic improvement and corrected blepharoptosis.  The authors concluded that resection through a lower eyebrow and coronal incision and levator resection performed in 2 stages can quickly correct the visual impairment caused by peri-orbital microcystic LM with blepharoptosis.  They stated that intralesional bleomycin injection is a promising adjunctive therapy for residual or recurrent lesions after surgery.

Intralesional corticosteroids injection

intralesional corticosteroids injection

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