In rabbits, fetal weight reduction and cleft palate were observed at a fluticasone propionate dose approximately times the MRHDID for adults (on a mg/m² basis at a maternal subcutaneous dose of 4 mcg/kg/day). However, no teratogenic effects were reported at fluticasone propionate doses up to approximately 20 times the MRHDID for adults (on a mg/m² basis at a maternal oral dose up to 300 mcg/kg/day). No fluticasone propionate was detected in the plasma in this study, consistent with the established low bioavailability following oral administration [see CLINICAL PHARMACOLOGY ].
Over the last four years, I’ve taken two courses of BEG spray – got re-infected after the initial treatment. I herxed mildly (flu symptoms) about three days after starting the spray and it lasted a few days. The spray did sting a bit at first (keep in the refrigerator to reduce stinging) and my nose was very runny the entire time – the result of the biofilm breaking down . Also, there was a slight increase in the ringing in my ears during treatment and near the end of the six weeks I was hit with a wall of super intense joint and muscle pain. I attributed the pain to toxins released by an excess of “bad” microbes (excess yeast and fungi) resulting from the killing off bacteria in my gut with the antibiotics.