Wheeler is a retired American IFBB professional bodybuilder. He won the Arnold Classic, which was a record five times, and was described by Arnold Schwarzenegger as one of the greatest bodybuilders he had ever seen. He had placed second at the 1993 Mr. Olympia, something he did again in 1998 and 1999. To date, he is a 5-time Ironman Pro winner, 4-time Arnold Classic winner, and has won the France Grand Prix, South Beach Pro Invitational, Night of Champions, and Hungarian Grand Prix. In 1999, he found out that he had focal segmental glomerulosclerosis, which is a form of kidney disease. Wheeler said that the condition is hereditary, although many believe it is from drug use that probably accelerated its onset.