I had what was called by doctors an eczema for almost two years, the only way of avoing that my face became full of a painful and odd locking rash (I cant even describe it) was to use creams with steroids or cortisone witch even doctors say it cant be use for a long period of time because causes the skin to became thinner and thinner. I had no other choice to continuously use it because the rash is unbearable. The steroid creams didn't let the rash appear (only if I stopped them for 3 days) but my nose area become to 'peel off' for almost 2 months continuously and with visible dry looking skin peeling off in some areas of the nose that not even Vaseline could help not showing.
Systemic ketoconazole is excreted in breast milk. In a case report of a mother prescribed 200 mg PO daily for 10 days, ketoconazole milk concentrations of mcg/mL (peak) were observed hours post-dose and were undetectable at 24 hours post-dose. Assuming a milk intake of 150 mL/kg/day, the daily ketoconazole dose of an exclusively breast-fed infant was calculated as mg/kg/day or % of the mother's weight-adjusted dose. The manufacturer recommends mothers refrain from breast-feeding their infants during oral therapy; however, previous American Academy of Pediatrics (AAP) recommendations considered ketoconazole compatible with breast-feeding. There are no adequate and well-controlled studies of topical use in nursing women; however, ketoconazole is not detected in plasma after chronic shampooing on the scalp. If the topical gel is used during breast-feeding and is applied to the chest, care should be taken to avoid accidental ingestion by the infant. Fluconazole may be a potential alternative to consider during breast-feeding. However, site of infection, patient factors, local susceptibility patterns, and specific microbial susceptibility should be assessed before choosing an alternative agent. Consider the benefits of breast-feeding, the risk of potential infant drug exposure, and the risk of an untreated or inadequately treated condition.